importantSYS.SOURCE: Ground Truths• 2026-10-01T20:02:57Z
Loss of Cell Identity as a Driver of Human Aging: Insights from Recent Research
Two studies propose that loss of cell identity, driven by erosion of epigenetic constraints like PRC2, underlies aging, with potential interventions including caloric restriction and partial reprogramming. Epigenetic clocks now correlate with PRC2 activity, offering new insights into aging mechanisms and therapeutic strategies.
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