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importantSYS.SOURCE: X2026-08-19T13:33:35Z

Moderna Reports First Positive Phase 3 Results for Individualized mRNA Neoantigen Therapy in Melanoma

Moderna and Merck reported positive Phase 3 results for intismeran autogene, an individualized mRNA neoantigen therapy for melanoma, in combination with KEYTRUDA, meeting primary and secondary endpoints. This marks the first positive Phase 3 outcome for an mRNA-based cancer therapy and an individualized neoantigen approach.

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